Why are HIV-1 fusion inhibitors not effective against SARS-CoV? Biophysical evaluation of molecular interactions

The envelope spike (S) glycoprotein of the severe acute respiratory syndrome associated coronavirus (SARS-CoV) mediates the entry of the virus into target cells. Recent studies point out to a cell entry mechanism of this virus similar to other enveloped viruses, such as HIV-1. As it happens with oth...

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Detalles Bibliográficos
Autores principales: Veiga, Salomé, Yuan, Yunyun, Li, Xuqin, Santos, Nuno C., Liu, Gang, Castanho, Miguel A.R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116955/
https://www.ncbi.nlm.nih.gov/pubmed/16290276
http://dx.doi.org/10.1016/j.bbagen.2005.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116955/
https://www.ncbi.nlm.nih.gov/pubmed/16290276
http://dx.doi.org/10.1016/j.bbagen.2005.10.001

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