Cargando…
Why are HIV-1 fusion inhibitors not effective against SARS-CoV? Biophysical evaluation of molecular interactions
The envelope spike (S) glycoprotein of the severe acute respiratory syndrome associated coronavirus (SARS-CoV) mediates the entry of the virus into target cells. Recent studies point out to a cell entry mechanism of this virus similar to other enveloped viruses, such as HIV-1. As it happens with oth...
Autores principales: | Veiga, Salomé, Yuan, Yunyun, Li, Xuqin, Santos, Nuno C., Liu, Gang, Castanho, Miguel A.R.B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116955/ https://www.ncbi.nlm.nih.gov/pubmed/16290276 http://dx.doi.org/10.1016/j.bbagen.2005.10.001 |
Ejemplares similares
-
HIV-1 Fusion Inhibitor Peptides Enfuvirtide and T-1249 Interact with Erythrocyte and Lymphocyte Membranes
por: Matos, Pedro M., et al.
Publicado: (2010) -
Parainfluenza Fusion Peptide Promotes Membrane Fusion
by Assembling into Oligomeric Porelike Structures
por: Valério, Mariana, et al.
Publicado: (2022) -
Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides
por: Mathieu, Cyrille, et al.
Publicado: (2017) -
Conjugation of Cholesterol to HIV-1 Fusion Inhibitor C34 Increases Peptide-Membrane Interactions Potentiating Its Action
por: Hollmann, Axel, et al.
Publicado: (2013) -
In and Out — Biochemical and Biophysical Mechanisms of Viral Fusion and Assembly
por: Santos, Nuno C.
Publicado: (2010)