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BAG3 down-modulation sensitizes HPV18(+) HeLa cells to PEITC-induced apoptosis and restores p53

BAG3 is a multi-functional component of tumor cell pro-survival machinery, and its biological functions have been largely associated to proteasome system. Here, we show that BAG3 down-modulation resulted in reduced cell viability and enhanced PEITC-induced apoptosis largely more extensively in HeLa...

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Detalles Bibliográficos
Autores principales: Cotugno, Roberta, Basile, Anna, Romano, Elena, Gallotta, Dario, Belisario, Maria Antonietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ireland Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116956/
https://www.ncbi.nlm.nih.gov/pubmed/25175321
http://dx.doi.org/10.1016/j.canlet.2014.08.022