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Viral models of multiple sclerosis: Neurodegeneration and demyelination in mice infected with Theiler's virus

Multiple sclerosis (MS) is a complex inflammatory disease of unknown etiology that affects the central nervous system (CNS) white matter, and for which no effective cure exists. Indeed, whether the primary event in MS pathology affects myelin or axons of the CNS remains unclear. Animal models are ne...

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Detalles Bibliográficos
Autores principales: Mecha, Miriam, Carrillo-Salinas, Francisco J., Mestre, Leyre, Feliú, Ana, Guaza, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117056/
https://www.ncbi.nlm.nih.gov/pubmed/23201558
http://dx.doi.org/10.1016/j.pneurobio.2012.11.003