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Assessment of the safety and efficacy of an attenuated live vaccine based on highly virulent genotype 2b porcine epidemic diarrhea virus in nursing piglets

We have previously reported the generation of the attenuated KNU-141112-S DEL5/ORF3 virus by continuous propagation of highly virulent G2b porcine epidemic diarrhea virus (PEDV) in Vero cells. The present study aimed to assess the safety of S DEL5/ORF3 and to evaluate its effectiveness as a live vac...

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Detalles Bibliográficos
Autores principales: Jang, Guehwan, Won, Hokeun, Lee, Dong-Uk, Noh, Yun-Hee, Lee, Seung-Chul, Choi, Hwan-Won, Yoon, In-Joong, Lee, Yoo Jin, Sang Yoo, Han, Lee, Changhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117296/
https://www.ncbi.nlm.nih.gov/pubmed/30955799
http://dx.doi.org/10.1016/j.vetmic.2019.03.009