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Establishment of an immunoscreening system using recombinant VP1 protein for the isolation of a monoclonal antibody that blocks JC virus infection

Polyomavirus JC (JCV) infection causes the fatal human demyelinating disease, progressive multifocal leukoencephalopathy. Although the initial interaction of JCV with host cells occurs through direct binding of the major viral capsid protein (VP1) with cell-surface molecules possessing sialic acid,...

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Detalles Bibliográficos
Autores principales: Henmi, Chizuka, Sawa, Hirofumi, Iwata, Hiroshi, Orba, Yasuko, Tanaka, Shinya, Nagashima, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117536/
https://www.ncbi.nlm.nih.gov/pubmed/15629455
http://dx.doi.org/10.1016/j.bbrc.2004.11.158