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Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage

Although porcine epidemic diarrhea (PED) has caused huge economic losses in the pork industry worldwide, an effective live, attenuated vaccine is lacking. In this study, an original US, highly virulent PED virus (PEDV) strain PC22A was serially passaged in Vero CCL81 and Vero BI cells. The virus gro...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Ming, Hou, Yixuan, Marthaler, Douglas G., Gao, Xiang, Liu, Xinsheng, Zheng, Lanlan, Saif, Linda J., Wang, Qiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117544/
https://www.ncbi.nlm.nih.gov/pubmed/28284624
http://dx.doi.org/10.1016/j.vetmic.2017.01.015