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Genetic deletion of Autotaxin from CD11b(+) cells decreases the severity of experimental autoimmune encephalomyelitis
Autotaxin (ATX) is a secreted lysophospholipase D catalyzing the extracellular production of lysophosphatidic acid (LPA), a growth factor-like signaling lysophospholipid. ATX and LPA signaling have been incriminated in the pathogenesis of different chronic inflammatory diseases and various types of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117669/ https://www.ncbi.nlm.nih.gov/pubmed/32240164 http://dx.doi.org/10.1371/journal.pone.0226050 |