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IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics

Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory, IL-17-secreting T cells (Th17 and Tγδ17) that play a key role in the development of inflammatory diseases. However, the IL-23 signaling cascade remains largely undefined. Here, we used quantitative phosphoproteomics to characte...

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Detalles Bibliográficos
Autores principales: Álvarez-Salamero, Candelas, Castillo-González, Raquel, Pastor-Fernández, Gloria, Mariblanca, Isabel R., Pino, Jesús, Cibrian, Danay, Navarro, María N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117768/
https://www.ncbi.nlm.nih.gov/pubmed/32203518
http://dx.doi.org/10.1371/journal.pbio.3000646