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The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion

Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in C. elegans is an excellent in vivo model to study the regulation of cell...

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Detalles Bibliográficos
Autores principales: Deng, Ting, Stempor, Przemyslaw, Appert, Alex, Daube, Michael, Ahringer, Julie, Hajnal, Alex, Lattmann, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117773/
https://www.ncbi.nlm.nih.gov/pubmed/32203506
http://dx.doi.org/10.1371/journal.pgen.1008470