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The MHCII peptidome of the pancreatic islet identifies key features of autoimmune peptides
The nature of autoantigens that trigger autoimmune diseases has been much discussed, but direct biochemical identification is lacking for most. Addressing this question demands unbiased examination of the self-peptides displayed by a defined autoimmune major histocompatibility complex class II (MHCI...
Autores principales: | Wan, Xiaoxiao, Vomund, Anthony N., Peterson, Orion J., Chervonsky, Alexander V., Lichti, Cheryl F., Unanue, Emil R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117798/ https://www.ncbi.nlm.nih.gov/pubmed/32152506 http://dx.doi.org/10.1038/s41590-020-0623-7 |
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