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Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes
The spindle generates force to segregate chromosomes at cell division. In mammalian cells, kinetochore-fibers connect chromosomes to the spindle. The dynamic spindle anchors kinetochore-fibers in space and time to move chromosomes. Yet, how it does so remains poorly understood as we lack tools to di...
Autores principales: | Suresh, Pooja, Long, Alexandra F, Dumont, Sophie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117910/ https://www.ncbi.nlm.nih.gov/pubmed/32191206 http://dx.doi.org/10.7554/eLife.53807 |
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