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Reduced Influence of apoE on Aβ43 Aggregation and Reduced Vascular Aβ43 Toxicity as Compared with Aβ40 and Aβ42

The amyloid-β 43 (Aβ43) peptide has been shown to be abundantly expressed in Alzheimer’s disease plaques, whereas only relatively low levels have been demonstrated in cerebral amyloid angiopathy (CAA). To better understand this discrepant distribution, we studied various biochemical properties of Aβ...

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Detalles Bibliográficos
Autores principales: Jäkel, Lieke, Biemans, Elisanne A.L.M., Klijn, Catharina J.M., Kuiperij, H. Bea, Verbeek, Marcel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118029/
https://www.ncbi.nlm.nih.gov/pubmed/31953617
http://dx.doi.org/10.1007/s12035-020-01873-x