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Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington’s Disease: a Longitudinal PET Study

Impairment of group I metabotropic glutamate receptors (mGluRs) results in altered glutamate signalling, which is associated with several neurological disorders including Huntington’s Disease (HD), an autosomal neurodegenerative disease. In this study, we assessed in vivo pathological changes in mGl...

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Detalles Bibliográficos
Autores principales: Bertoglio, Daniele, Verhaeghe, Jeroen, Korat, Špela, Miranda, Alan, Cybulska, Klaudia, Wyffels, Leonie, Stroobants, Sigrid, Mrzljak, Ladislav, Dominguez, Celia, Skinbjerg, Mette, Liu, Longbin, Munoz-Sanjuan, Ignacio, Staelens, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118044/
https://www.ncbi.nlm.nih.gov/pubmed/31912442
http://dx.doi.org/10.1007/s12035-019-01866-5