Cargando…
Ancestry deconvolution and partial polygenic score can improve susceptibility predictions in recently admixed individuals
Polygenic Scores (PSs) describe the genetic component of an individual’s quantitative phenotype or their susceptibility to diseases with a genetic basis. Currently, PSs rely on population-dependent contributions of many associated alleles, with limited applicability to understudied populations and r...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118071/ https://www.ncbi.nlm.nih.gov/pubmed/32242022 http://dx.doi.org/10.1038/s41467-020-15464-w |