Tumor-penetrating peptide for systemic targeting of Tenascin-C

Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C (TNC-C) upregulated in malignant tissues. TNC-C binding PL3 peptide (amino...

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Detalles Bibliográficos
Autores principales: Lingasamy, Prakash, Tobi, Allan, Kurm, Kaarel, Kopanchuk, Sergei, Sudakov, Aleksander, Salumäe, Markko, Rätsep, Tõnu, Asser, Toomas, Bjerkvig, Rolf, Teesalu, Tambet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118115/
https://www.ncbi.nlm.nih.gov/pubmed/32242067
http://dx.doi.org/10.1038/s41598-020-62760-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118115/
https://www.ncbi.nlm.nih.gov/pubmed/32242067
http://dx.doi.org/10.1038/s41598-020-62760-y

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