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Tumor-penetrating peptide for systemic targeting of Tenascin-C
Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C (TNC-C) upregulated in malignant tissues. TNC-C binding PL3 peptide (amino...
Autores principales: | Lingasamy, Prakash, Tobi, Allan, Kurm, Kaarel, Kopanchuk, Sergei, Sudakov, Aleksander, Salumäe, Markko, Rätsep, Tõnu, Asser, Toomas, Bjerkvig, Rolf, Teesalu, Tambet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118115/ https://www.ncbi.nlm.nih.gov/pubmed/32242067 http://dx.doi.org/10.1038/s41598-020-62760-y |
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