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Chronology of cellular events related to mitochondrial burnout leading to cell death in Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is a degenerative eye disease characterized by corneal endothelial cell (CEC) death and the formation of guttae, an abnormal thickening of CEC’s basement membrane. At the tissue level, an oxidative stress causing mitochondrial damage and CEC death have been...

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Detalles Bibliográficos
Autores principales: Méthot, Sébastien J., Proulx, Stéphanie, Brunette, Isabelle, Rochette, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118119/
https://www.ncbi.nlm.nih.gov/pubmed/32242036
http://dx.doi.org/10.1038/s41598-020-62602-x