Cargando…
Evidence for functional selectivity in TUDC- and norUDCA-induced signal transduction via α(5)β(1) integrin towards choleresis
Functional selectivity is the ligand-specific activation of certain signal transduction pathways at a receptor and has been described for G protein-coupled receptors. However, it has not yet been described for ligands interacting with integrins without αI domain. Here, we show by molecular dynamics...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118123/ https://www.ncbi.nlm.nih.gov/pubmed/32242141 http://dx.doi.org/10.1038/s41598-020-62326-y |