Cargando…

TNIK signaling imprints CD8(+) T cell memory formation early after priming

Co-stimulatory signals, cytokines and transcription factors regulate the balance between effector and memory cell differentiation during T cell activation. Here, we analyse the role of the TRAF2-/NCK-interacting kinase (TNIK), a signaling molecule downstream of the tumor necrosis factor superfamily...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaeger-Ruckstuhl, Carla A., Hinterbrandner, Magdalena, Höpner, Sabine, Correnti, Colin E., Lüthi, Ursina, Friedli, Olivier, Freigang, Stefan, Al Sayed, Mohamad F., Bührer, Elias D., Amrein, Michael A., Schürch, Christian M., Radpour, Ramin, Riether, Carsten, Ochsenbein, Adrian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118140/
https://www.ncbi.nlm.nih.gov/pubmed/32242021
http://dx.doi.org/10.1038/s41467-020-15413-7