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TNIK signaling imprints CD8(+) T cell memory formation early after priming
Co-stimulatory signals, cytokines and transcription factors regulate the balance between effector and memory cell differentiation during T cell activation. Here, we analyse the role of the TRAF2-/NCK-interacting kinase (TNIK), a signaling molecule downstream of the tumor necrosis factor superfamily...
Autores principales: | Jaeger-Ruckstuhl, Carla A., Hinterbrandner, Magdalena, Höpner, Sabine, Correnti, Colin E., Lüthi, Ursina, Friedli, Olivier, Freigang, Stefan, Al Sayed, Mohamad F., Bührer, Elias D., Amrein, Michael A., Schürch, Christian M., Radpour, Ramin, Riether, Carsten, Ochsenbein, Adrian F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118140/ https://www.ncbi.nlm.nih.gov/pubmed/32242021 http://dx.doi.org/10.1038/s41467-020-15413-7 |
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