Pan-cancer molecular analysis of the RB tumor suppressor pathway

The retinoblastoma tumor suppressor gene (RB1) plays a critical role in coordinating multiple pathways that impact cancer initiation, disease progression, and therapeutic responses. Here we probed molecular features associated with the RB-pathway across 31 tumor-types. While the RB-pathway has been...

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Detalles Bibliográficos
Autores principales: Knudsen, Erik S., Nambiar, Ram, Rosario, Spencer R., Smiraglia, Dominic J., Goodrich, David W., Witkiewicz, Agnieszka K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118159/
https://www.ncbi.nlm.nih.gov/pubmed/32242058
http://dx.doi.org/10.1038/s42003-020-0873-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118159/
https://www.ncbi.nlm.nih.gov/pubmed/32242058
http://dx.doi.org/10.1038/s42003-020-0873-9

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