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Pan-cancer molecular analysis of the RB tumor suppressor pathway
The retinoblastoma tumor suppressor gene (RB1) plays a critical role in coordinating multiple pathways that impact cancer initiation, disease progression, and therapeutic responses. Here we probed molecular features associated with the RB-pathway across 31 tumor-types. While the RB-pathway has been...
Autores principales: | Knudsen, Erik S., Nambiar, Ram, Rosario, Spencer R., Smiraglia, Dominic J., Goodrich, David W., Witkiewicz, Agnieszka K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118159/ https://www.ncbi.nlm.nih.gov/pubmed/32242058 http://dx.doi.org/10.1038/s42003-020-0873-9 |
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