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Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species

BACKGROUND: Pharmacokinetics provides a scientific basis for drug product design, dosage regimen planning, understanding the body's action on the drug, and relating the time course of the drug in the body to its pharmacodynamics and/or toxic effects. Recently, naringin, a natural flavonoid, was...

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Detalles Bibliográficos
Autores principales: Bai, Yang, Peng, Wei, Yang, Cuiping, Zou, Wei, Liu, Menghua, Wu, Hao, Fan, Loudi, Li, Peibo, Zeng, Xuan, Su, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118210/
https://www.ncbi.nlm.nih.gov/pubmed/32292344
http://dx.doi.org/10.3389/fphar.2020.00364