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Intracellular Selection of Theophylline-Sensitive Hammerhead Aptazyme

Hammerhead ribozyme-based aptazyme (HHAz), inheriting the advantages of small size and high efficiency from the RNA-cleaving ribozyme and the specific recognition ability of aptamers to specific targets, exhibits the huge potential to be a transgene expression regulator. Herein, we report a selectio...

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Detalles Bibliográficos
Autores principales: Pu, Qinlin, Zhou, Shan, Huang, Xin, Yuan, Yi, Du, Feng, Dong, Juan, Chen, Gangyi, Cui, Xin, Tang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118274/
https://www.ncbi.nlm.nih.gov/pubmed/32244167
http://dx.doi.org/10.1016/j.omtn.2020.03.001