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Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability

Various drug transporters are widely expressed throughout the intestine and play important roles in absorbing nutrients and drugs, thus providing high quality targets for the design of prodrugs or nanoparticles to facilitate oral drug delivery. In particular, intestinal carnitine/organic cation tran...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Zhao, Lichun, jiang, Qikun, Sun, Yixin, Zhao, Dongyang, Sun, Mengchi, He, Zhonggui, sun, Jin, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118283/
https://www.ncbi.nlm.nih.gov/pubmed/32256846
http://dx.doi.org/10.1016/j.ajps.2020.02.002