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Resveratrol Preincubation Enhances the Therapeutic Efficacy of hUC-MSCs by Improving Cell Migration and Modulating Neuroinflammation Mediated by MAPK Signaling in a Mouse Model of Alzheimer’s Disease

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are promising for the treatment of Alzheimer’s disease (AD). However, their low rate of migration and survival in the brain limit their clinical applicability. This study is designed to improve the therapeutic potential of hUC-MSCs by pr...

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Detalles Bibliográficos
Autores principales: Wang, Xinxin, Wu, Junwei, Ma, Shanshan, Xie, Ya, Liu, Hongtao, Yao, Minghao, Zhang, Yanting, Yang, Greta Luyuan, Yang, Bo, Guo, Ruixia, Guan, Fangxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118399/
https://www.ncbi.nlm.nih.gov/pubmed/32292331
http://dx.doi.org/10.3389/fncel.2020.00062