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Paracrine and cell autonomous signalling in pancreatic cancer progression and metastasis

Pancreatic ductal adenocarcinoma (PDAC) shows remarkable propensity to metastasize. This predilection to escape from the primary tumor is driven by paracrine and autocrine mechanisms that guide cancer cells through a multi-step process concluding with colonization in distant tissues. Although cell-i...

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Detalles Bibliográficos
Autores principales: Thomas, Stacy K., Lee, Jesse, Beatty, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118576/
https://www.ncbi.nlm.nih.gov/pubmed/32139180
http://dx.doi.org/10.1016/j.ebiom.2020.102662