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APOE-amyloid interaction: Therapeutic targets

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder that is growing in prevalence globally. It is the only major cause of death without any effective pharmacological means to treat or slow progression. Inheritance of the ε4 allele of the Apolipoprotein (APO) E gene is the strongest...

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Detalles Bibliográficos
Autores principales: Wisniewski, Thomas, Drummond, Eleanor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118587/
https://www.ncbi.nlm.nih.gov/pubmed/32027932
http://dx.doi.org/10.1016/j.nbd.2020.104784