Aldehyde Dehydrogenase 2 Protects Against Post-Cardiac Arrest Myocardial Dysfunction Through a Novel Mechanism of Suppressing Mitochondrial Reactive Oxygen Species Production

Post-cardiac arrest myocardial dysfunction significantly contributes to early mortality after the return of spontaneous circulation. However, no effective therapy is available now. Aldehyde dehydrogenase 2 (ALDH2) enzyme has been shown to protect the heart from aldehyde toxicity such as 4-hydroxy-2-...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Liu, Baoshan, Fan, Xinhui, Wang, Wenjun, Xu, Tonghui, Wei, Shujian, Zheng, Wen, Yuan, Qiuhuan, Gao, Luyao, Yin, Xinxin, Zheng, Boyuan, Zhang, Chuanxin, Zhang, Shuai, Yang, Kehui, Xue, Mengyang, Wang, Shuo, Xu, Feng, Wang, Jiali, Cao, Yihai, Chen, Yuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118728/
https://www.ncbi.nlm.nih.gov/pubmed/32292348
http://dx.doi.org/10.3389/fphar.2020.00373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118728/
https://www.ncbi.nlm.nih.gov/pubmed/32292348
http://dx.doi.org/10.3389/fphar.2020.00373

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