Disease-Associated Mutant Tau Prevents Circadian Changes in the Cytoskeleton of Central Pacemaker Neurons

A hallmark feature of Alzheimer’s disease (AD) and other Tauopathies, like Frontotemporal Dementia with Parkinsonism linked to chromosome 17 (FTDP-17), is the accumulation of neurofibrillary tangles composed of the microtubule-associated protein Tau. As in AD, symptoms of FTDP-17 include cognitive d...

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Detalles Bibliográficos
Autores principales: Cassar, Marlène, Law, Alexander D., Chow, Eileen S., Giebultowicz, Jadwiga M., Kretzschmar, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118733/
https://www.ncbi.nlm.nih.gov/pubmed/32292325
http://dx.doi.org/10.3389/fnins.2020.00232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118733/
https://www.ncbi.nlm.nih.gov/pubmed/32292325
http://dx.doi.org/10.3389/fnins.2020.00232

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