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Innate and Adaptive Immunity through Autophagy

The two main proteolytic machineries of eukaryotic cells, lysosomes and proteasomes, receive substrates by different routes. Polyubiquitination targets proteins for proteasomal degradation, whereas autophagy delivers intracellular material for lysosomal hydrolysis. The importance of autophagy for ce...

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Detalles Bibliográficos
Autores principales: Schmid, Dorothee, Münz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118777/
https://www.ncbi.nlm.nih.gov/pubmed/17663981
http://dx.doi.org/10.1016/j.immuni.2007.07.004