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Innate and Adaptive Immunity through Autophagy
The two main proteolytic machineries of eukaryotic cells, lysosomes and proteasomes, receive substrates by different routes. Polyubiquitination targets proteins for proteasomal degradation, whereas autophagy delivers intracellular material for lysosomal hydrolysis. The importance of autophagy for ce...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Inc.
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118777/ https://www.ncbi.nlm.nih.gov/pubmed/17663981 http://dx.doi.org/10.1016/j.immuni.2007.07.004 |