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Adaptive Fisher method detects dense and sparse signals in association analysis of SNV sets
BACKGROUND: With the development of next generation sequencing (NGS) technology and genotype imputation methods, statistical methods have been proposed to test a set of genomic variants together to detect if any of them is associated with the phenotype or disease. In practice, within the set, there...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118831/ https://www.ncbi.nlm.nih.gov/pubmed/32241265 http://dx.doi.org/10.1186/s12920-020-0684-3 |