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Adaptive Fisher method detects dense and sparse signals in association analysis of SNV sets

BACKGROUND: With the development of next generation sequencing (NGS) technology and genotype imputation methods, statistical methods have been proposed to test a set of genomic variants together to detect if any of them is associated with the phenotype or disease. In practice, within the set, there...

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Detalles Bibliográficos
Autores principales: Cai, Xiaoyu, Chang, Lo-Bin, Potter, Jordan, Song, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118831/
https://www.ncbi.nlm.nih.gov/pubmed/32241265
http://dx.doi.org/10.1186/s12920-020-0684-3