Cargando…
ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection
BACKGROUND: Neoantigens can be differentially recognized by T cell receptor (TCR) as these sequences are derived from mutant proteins and are unique to the tumor. The discovery of neoantigens is the first key step for tumor-specific antigen (TSA) based immunotherapy. Based on high-throughput tumor g...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118832/ https://www.ncbi.nlm.nih.gov/pubmed/32241270 http://dx.doi.org/10.1186/s12920-020-0683-4 |