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ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection
BACKGROUND: Neoantigens can be differentially recognized by T cell receptor (TCR) as these sequences are derived from mutant proteins and are unique to the tumor. The discovery of neoantigens is the first key step for tumor-specific antigen (TSA) based immunotherapy. Based on high-throughput tumor g...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118832/ https://www.ncbi.nlm.nih.gov/pubmed/32241270 http://dx.doi.org/10.1186/s12920-020-0683-4 |