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Optimizing the refolding conditions of self-assembling polypeptide nanoparticles that serve as repetitive antigen display systems
Nanoparticles show great promise as potent vaccine candidates since they are readily taken up by the antigen presenting cells of the immune system. The particle size and the density of the B cell epitopes on the surface of the particles greatly influences the strength of the humoral immune response....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118850/ https://www.ncbi.nlm.nih.gov/pubmed/22115997 http://dx.doi.org/10.1016/j.jsb.2011.11.011 |