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The OC43 human coronavirus envelope protein is critical for infectious virus production and propagation in neuronal cells and is a determinant of neurovirulence and CNS pathology

The OC43 strain of human coronavirus (HCoV-OC43) is an ubiquitous respiratory tract pathogen possessing neurotropic capacities. Coronavirus structural envelope (E) protein possesses specific motifs involved in protein-protein interaction or in homo-oligomeric ion channel formation, which are known t...

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Detalles Bibliográficos
Autores principales: Stodola, Jenny K., Dubois, Guillaume, Le Coupanec, Alain, Desforges, Marc, Talbot, Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118982/
https://www.ncbi.nlm.nih.gov/pubmed/29287230
http://dx.doi.org/10.1016/j.virol.2017.12.023