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Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers

Enterovirus 71 (EV-71) infections are generally manifested as mild hand, foot and mouth disease, but have been reported to cause severe neurological complications with high mortality rates. Treatment options remain limited due to the lack of antivirals. Octaguanidinium-conjugated morpholino oligomer...

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Detalles Bibliográficos
Autores principales: Tan, Chee Wah, Chan, Yoke Fun, Quah, Yi Wan, Poh, Chit Laa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118997/
https://www.ncbi.nlm.nih.gov/pubmed/24769243
http://dx.doi.org/10.1016/j.antiviral.2014.04.004