Discovering novel chemical inhibitors of human cyclophilin A: Virtual screening, synthesis, and bioassay

Cyclophilin A (CypA) is a member of cyclophilins, a family of the highly homologous peptidyl prolyl cis–trans isomerases (PPIases), which can bind to cyclosporin A (CsA). CypA plays critical roles in various biological processes, including protein folding, assembly, transportation, regulation of neu...

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Detalles Bibliográficos
Autores principales: Li, Jian, Chen, Jing, Gui, Chunshan, Zhang, Li, Qin, Yu, Xu, Qiang, Zhang, Jian, Liu, Hong, Shen, Xu, Jiang, Hualiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119052/
https://www.ncbi.nlm.nih.gov/pubmed/16307882
http://dx.doi.org/10.1016/j.bmc.2005.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119052/
https://www.ncbi.nlm.nih.gov/pubmed/16307882
http://dx.doi.org/10.1016/j.bmc.2005.11.006

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