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Discovering novel chemical inhibitors of human cyclophilin A: Virtual screening, synthesis, and bioassay

Cyclophilin A (CypA) is a member of cyclophilins, a family of the highly homologous peptidyl prolyl cis–trans isomerases (PPIases), which can bind to cyclosporin A (CsA). CypA plays critical roles in various biological processes, including protein folding, assembly, transportation, regulation of neu...

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Detalles Bibliográficos
Autores principales:	Li, Jian, Chen, Jing, Gui, Chunshan, Zhang, Li, Qin, Yu, Xu, Qiang, Zhang, Jian, Liu, Hong, Shen, Xu, Jiang, Hualiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119052/ https://www.ncbi.nlm.nih.gov/pubmed/16307882 http://dx.doi.org/10.1016/j.bmc.2005.11.006

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