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Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition
The secretory pathway in cells possesses an elaborate set of endoproteolytic enzymes that carry out a crucial step in protein precursor maturation. This step is proteolytic activation by cleavage at specific pairs of basic residues. These enzymes, named pro-protein convertases (PCs), are responsible...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119077/ https://www.ncbi.nlm.nih.gov/pubmed/15925704 http://dx.doi.org/10.1016/j.tips.2005.04.006 |