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Autophagy Induced by Proteasomal DUB Inhibitor NiPT Restricts NiPT-Mediated Cancer Cell Death

Ubiquitin–proteasome system (UPS) and autophagy–lysosome pathway (ALP) are two major systems for protein quality control (PQC) in eukaryotic cells. Interconnectivity between these two pathways has been suggested, but the molecular detail of how they impact each other remains elusive. Proteasomal deu...

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Detalles Bibliográficos
Autores principales: Chen, Jinghong, Chen, Xin, Xu, Dacai, Yang, Li, Yang, Zhenjun, Yang, Qianqian, Yan, Ding, Zhang, Peiquan, Feng, Du, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119081/
https://www.ncbi.nlm.nih.gov/pubmed/32292717
http://dx.doi.org/10.3389/fonc.2020.00348