Tetrabutylammonium fluoride-assisted rapid N(9)-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ

Tremendous efforts have been invested in the synthesis of purine libraries due to their importance in targeting various enzymes involved in different diseases and cellular processes. The synthesis of N(9)-alkylated purine scaffolds relied mostly on Mitsunobu conditions with a variety of alcohols or...

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Detalles Bibliográficos
Autores principales: Brik, Ashraf, Wu, Chung-Yi, Best, Michael D., Wong, Chi-Huey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119094/
https://www.ncbi.nlm.nih.gov/pubmed/15953729
http://dx.doi.org/10.1016/j.bmc.2005.02.066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119094/
https://www.ncbi.nlm.nih.gov/pubmed/15953729
http://dx.doi.org/10.1016/j.bmc.2005.02.066

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