From genome to drug lead: Identification of a small-molecule inhibitor of the SARS virus

Virtual screening, a fast, computational approach to identify drug leads [Perola, E.; Xu, K.; Kollmeyer, T. M.; Kaufmann, S. H.; Prendergast, F. G. J. Med. Chem.2000, 43, 401; Miller, M. A. Nat. Rev. Drug Disc.2002, 1 220], is limited by a known challenge in crystallographically determining flexible...

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Detalles Bibliográficos
Autores principales: Dooley, Andrea J., Shindo, Nice, Taggart, Barbara, Park, Jewn-Giew, Pang, Yuan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119130/
https://www.ncbi.nlm.nih.gov/pubmed/16325400
http://dx.doi.org/10.1016/j.bmcl.2005.11.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119130/
https://www.ncbi.nlm.nih.gov/pubmed/16325400
http://dx.doi.org/10.1016/j.bmcl.2005.11.018

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