Inhibition of hepatitis B virus replication by ligand-mediated activation of RNase L

RNase L is a cellular endoribonuclease that is activated by 2′,5′-linked oligoadenylates (2–5A), which are unique and specific ligands synthesized by a family of interferon-inducible, dsRNA-activated enzymes named oligoadenylate synthetases. In the typical antiviral pathway, activated RNase L degrad...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Il-Hyun, Kwon, Young-Chan, Ryu, Wang-Shick, Ahn, Byung-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119188/
https://www.ncbi.nlm.nih.gov/pubmed/24509240
http://dx.doi.org/10.1016/j.antiviral.2014.01.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119188/
https://www.ncbi.nlm.nih.gov/pubmed/24509240
http://dx.doi.org/10.1016/j.antiviral.2014.01.021

Ejemplares similares