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Recognizing and stabilizing miR-21 by chiral ruthenium(II) complexes

MiR-21, a non-coding miRNA with 22 nucleotides, plays an important part in the proliferation, invasion, and metastasis of tumor cells. The present study demonstrates that isomers of chiral ruthenium(II) complexes with alkynes (Λ-1 and Δ-1) were synthesized by Songogashira coupling reaction by using...

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Detalles Bibliográficos
Autores principales: Feng, Yin, Shu, Jing, Yao, Liangzhong, Lan, Yutao, Ye, Lianbao, Mei, Wenjie, Ding, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119291/
https://www.ncbi.nlm.nih.gov/pubmed/32266333
http://dx.doi.org/10.1186/s13065-020-00672-8