Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma

BACKGROUND: Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. METHODS: We explored the role of somatic synonymous mutations in melanoma...

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Detalles Bibliográficos
Autores principales: Zhang, Di, Xia, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119296/
https://www.ncbi.nlm.nih.gov/pubmed/32241263
http://dx.doi.org/10.1186/s12920-020-0685-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119296/
https://www.ncbi.nlm.nih.gov/pubmed/32241263
http://dx.doi.org/10.1186/s12920-020-0685-2

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