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Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma
BACKGROUND: Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. METHODS: We explored the role of somatic synonymous mutations in melanoma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119296/ https://www.ncbi.nlm.nih.gov/pubmed/32241263 http://dx.doi.org/10.1186/s12920-020-0685-2 |