The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

The biological significance of deadenylation in global gene expression is not fully understood. Here, we show that the CCR4–NOT deadenylase complex maintains expression of mRNAs, such as those encoding transcription factors, cell cycle regulators, DNA damage response–related proteins, and metabolic...

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Detalles Bibliográficos
Autores principales: Takahashi, Akinori, Suzuki, Toru, Soeda, Shou, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Mohamed, Haytham Mohamed Aly, Yanagiya, Akiko, Abe, Takaya, Shigeta, Mayo, Furuta, Yasuhide, Kuba, Keiji, Yamamoto, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119370/
https://www.ncbi.nlm.nih.gov/pubmed/32238456
http://dx.doi.org/10.26508/lsa.201900494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7119370/
https://www.ncbi.nlm.nih.gov/pubmed/32238456
http://dx.doi.org/10.26508/lsa.201900494

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